Projects

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In my main PhD project, I focused on RNA binding proteins (RBPs) and their role in RNA pathways. To better understand their functions, we selected RBPs based on their known involvement in these pathways and immunoprecipitated them. Through this approach, we were able to create a function-based network that allowed us to assign new functionalities to both known and novel RBPs. Our work on this project was recently presented at CSAMA 2022.

For my M.Sc project, I developed a scoring function to evaluate the performance of four widely used RNA-Seq differential expression packages (DESeq2, edgeR, limma+voom, and BaySeq). The aim was to compare and assess the results of each package and determine the optimal approach for detecting differentially expressed genes (DEGs). By developing this function, we aimed to provide researchers with a tool to maximize or restrict the number of detected DEGs based on their criteria.